What happens when you stop taking creatine?

When you stop taking creatine, the extra creatine in your muscles slowly drops back to your normal level over about 4–6 weeks, and the water stored with it leaves too. Your stores do not fall below where you started, and your body’s own creatine production returns. You can stop at any time without tapering.

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Key takeaways

What happens when you stop taking creatine?

Creatine works by raising the amount stored in your muscles. When you stop, nothing happens on the first day. Your muscles keep the extra creatine for a while, and a small amount is broken down each day and removed as creatinine in urine. Over the following weeks, stores drift back to their normal, unsupplemented level.

As stores fall, two things change:

How long does creatine take to leave your system?

About 4–6 weeks for muscle stores to return to baseline. The evidence for this timeline comes from a few classic studies:

Blood creatinine, a kidney lab marker that creatine can raise, is expected to drift back toward your usual level on a similar timeline. If you have a blood test coming up, tell your doctor you take creatine. Our creatinine blood test guide explains why.

Do you lose your gains when you stop creatine?

You lose the part that depends on extra creatine in the muscle: the water and the small performance boost. You do not lose muscle simply because you stopped a supplement.

Muscle tissue built through training is maintained by training and eating enough protein. If you keep training after stopping creatine, you may see a slight dip in reps or weight on the scale, but the muscle itself remains. If you stop training at the same time, you will lose some muscle and strength over time, and that would happen with or without creatine.

Research on exactly how much performance is kept after stopping creatine is limited, so be cautious about any precise claims.

Does your body stop making its own creatine?

It slows down while you supplement, then recovers. For people who eat meat, about half of the daily need for creatine comes from food, and the liver and kidneys make the rest. When you take creatine, the body makes less of its own. A 2015 trial found that 3 g a day for 12 weeks lowered blood levels of guanidinoacetate, the building block for creatine, by about 10%, which shows that the body’s own production slows down.

This is a normal feedback response, not damage. The ISSN position stand notes that there is no evidence that muscle creatine falls below baseline after supplementation stops, so long-term suppression of the body’s own production does not appear to occur.

Do you need to cycle creatine?

No. Cycling means taking creatine for a set period and then stopping for a few weeks. The idea is that a break lets the body "reset". The research summarized above does not show that the body needs a reset, and the standard approach is simply to take 3–5 g a day continuously. The ISSN position stand found no clinically significant side effects in studies following athletes for up to 3 years.

Taking a break is still fine if you want one, for example for travel, a pause in training, or personal preference. Just know that your stores will drift down over the following weeks. When you start again, you can use a loading phase to refill stores in about a week, or take 3–5 g a day and reach the same level in about three to four weeks.

Can you quit creatine cold turkey?

Yes. There is no need to taper the dose down. Creatine is not a stimulant or hormone, and stores fall gradually on their own after the last dose. We are not aware of research describing a withdrawal syndrome from stopping creatine. Some people notice slightly lower energy in hard training sessions in the weeks after stopping. That is most likely the loss of the performance boost, not withdrawal.

If a doctor told you to stop creatine, for example because of kidney disease or a pregnancy, follow that advice. If you have questions about a supplement and a prescribed medication, ask your clinician or pharmacist.

References

  1. Kreider RB, Kalman DS, Antonio J, et al. (2017). International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. Journal of the International Society of Sports Nutrition, 14:18. doi:10.1186/s12970-017-0173-z
  2. Hultman E, Söderlund K, Timmons JA, Cederblad G, Greenhaff PL (1996). Muscle creatine loading in men. Journal of Applied Physiology, 81(1):232–237. doi:10.1152/jappl.1996.81.1.232
  3. Vandenberghe K, Goris M, Van Hecke P, et al. (1997). Long-term creatine intake is beneficial to muscle performance during resistance training. Journal of Applied Physiology, 83(6):2055–2063. doi:10.1152/jappl.1997.83.6.2055
  4. Peters BA, Hall MN, Liu X, et al. (2015). Low-dose creatine supplementation lowers plasma guanidinoacetate, but not plasma homocysteine, in a double-blind, randomized, placebo-controlled trial. Journal of Nutrition, 145(10):2245–2252. Read the study

Common questions

How long does it take for creatine to leave your muscles?
Muscle creatine stores generally return to baseline about 4–6 weeks after you stop. In one classic study, levels were back to normal 30 days after supplementation ended.
Will I lose muscle if I stop taking creatine?
Not because of stopping creatine itself. You lose the extra water and the small performance boost, but muscle built through training stays if you keep training and eat enough protein.
Do you need to cycle off creatine?
No. The standard approach is 3–5 g a day taken continuously. Taking a break is fine, but it is not required.
Can you stop taking creatine cold turkey?
Yes. You do not need to taper. Muscle stores fall gradually on their own over several weeks after the last dose.
Does creatine stop your body from making creatine?
Your body makes less of its own creatine while you supplement, which is a normal feedback response. There is no evidence that stores fall below baseline after you stop, so this suppression does not appear to be long term.
Will I lose weight when I stop creatine?
You may lose a small amount of water weight over the following weeks as muscle creatine returns to normal. This is water, not fat or muscle.

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